Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
FCGR2A
Другие языки:
FCGR2A
Подписчиков: 0, рейтинг: 0
FCGR2A | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||||||
Mã định danh | |||||||||||||||||
Danh pháp | FCGR2A, CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2, Fc fragment of IgG receptor IIa, FcgammaRIIa, Fc gamma receptor IIa | ||||||||||||||||
ID ngoài | OMIM: 146790 HomoloGene: 47936 GeneCards: FCGR2A | ||||||||||||||||
| |||||||||||||||||
| |||||||||||||||||
Gen cùng nguồn | |||||||||||||||||
Loài | Người | Chuột | |||||||||||||||
Entrez |
|
||||||||||||||||
Ensembl |
|
||||||||||||||||
UniProt |
|
||||||||||||||||
RefSeq (mRNA) |
|
||||||||||||||||
RefSeq (protein) |
|
||||||||||||||||
Vị trí gen (UCSC) | n/a | n/a | |||||||||||||||
PubMed | n/a | ||||||||||||||||
Wikidata | |||||||||||||||||
|
Low affinity immunoglobulin gamma Fc region receptor II-a là protein ở người được mã hóa bởi gen FCGR2A.
Tương tác
FCGR2A có khả năng tương tác với PIK3R1 và Syk.
Xem thêm
Tham khảo
Đọc thêm
- McKenzie SE (2002). “Humanized mouse models of FcR clearance in immune platelet disorders”. Blood Rev. 16 (1): 3–5. doi:10.1054/blre.2001.0170. PMID 11913983.
- Ernst LK, van de Winkel JG, Chiu IM, Anderson CL (1992). “Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products”. J. Biol. Chem. 267 (22): 15692–700. PMID 1379234.
- Seki T (1989). “Identification of multiple isoforms of the low-affinity human IgG Fc receptor”. Immunogenetics. 30 (1): 5–12. doi:10.1007/BF02421463. PMID 2526077.
- Hessian PA, Highton J, Palmer DG (1989). “Quantification of macrophage cell surface molecules in rheumatoid arthritis”. Clin. Exp. Immunol. 77 (1): 47–51. PMC 1541930. PMID 2527651.
- Brooks DG, Qiu WQ, Luster AD, Ravetch JV (1989). “Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes”. J. Exp. Med. 170 (4): 1369–85. doi:10.1084/jem.170.4.1369. PMC 2189488. PMID 2529342.
- Lanier LL, Cwirla S, Yu G, và đồng nghiệp (1990). “Membrane anchoring of a human IgG Fc receptor (CD16) determined by a single amino acid”. Science. 246 (4937): 1611–3. doi:10.1126/science.2531919. PMID 2531919.
- Stuart SG, Trounstine ML, Vaux DJ, và đồng nghiệp (1987). “Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII)”. J. Exp. Med. 166 (6): 1668–84. doi:10.1084/jem.166.6.1668. PMC 2188792. PMID 2824655.
- Hibbs ML, Bonadonna L, Scott BM, và đồng nghiệp (1988). “Molecular cloning of a human immunoglobulin G Fc receptor”. Proc. Natl. Acad. Sci. U.S.A. 85 (7): 2240–4. doi:10.1073/pnas.85.7.2240. PMC 279966. PMID 2965389.
- Huizinga TW, van der Schoot CE, Jost C, và đồng nghiệp (1988). “The PI-linked receptor FcRIII is released on stimulation of neutrophils”. Nature. 333 (6174): 667–9. doi:10.1038/333667a0. PMID 2967437.
- Sammartino L, Webber LM, Hogarth PM, và đồng nghiệp (1988). “Assignment of the gene coding for human FcRII (CD32) to bands q23q24 on chromosome 1”. Immunogenetics. 28 (5): 380–1. doi:10.1007/BF00364238. PMID 2971615.
- Stengelin S, Stamenkovic I, Seed B (1988). “Isolation of cDNAs for two distinct human Fc receptors by ligand affinity cloning”. EMBO J. 7 (4): 1053–9. PMC 454434. PMID 3402431.
- Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Chacko GW, Brandt JT, Coggeshall KM, Anderson CL (1996). “Phosphoinositide 3-kinase and p72syk noncovalently associate with the low affinity Fc gamma receptor on human platelets through an immunoreceptor tyrosine-based activation motif. Reconstitution with synthetic phosphopeptides”. J. Biol. Chem. 271 (18): 10775–81. doi:10.1074/jbc.271.18.10775. PMID 8631888.
- Salmon JE, Millard S, Schachter LA, và đồng nghiệp (1996). “Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans”. J. Clin. Invest. 97 (5): 1348–54. doi:10.1172/JCI118552. PMC 507190. PMID 8636449.
- Bewarder N, Weinrich V, Budde P, và đồng nghiệp (1996). “In vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylation”. Mol. Cell. Biol. 16 (9): 4735–43. PMC 231474. PMID 8756631.
- Sármay G, Koncz G, Gergely J (1997). “Human type II Fcgamma receptors inhibit B cell activation by interacting with the p21(ras)-dependent pathway”. J. Biol. Chem. 271 (48): 30499–504. doi:10.1074/jbc.271.48.30499. PMID 8940017.
- Ibarrola I, Vossebeld PJ, Homburg CH, và đồng nghiệp (1997). “Influence of tyrosine phosphorylation on protein interaction with FcgammaRIIa”. Biochim. Biophys. Acta. 1357 (3): 348–58. doi:10.1016/S0167-4889(97)00034-7. PMID 9268059.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, và đồng nghiệp (1997). “Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library”. Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- De SK, Venkateshan CN, Seth P, và đồng nghiệp (1998). “Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcgamma receptors and expression of monokines”. Blood. 91 (6): 2108–17. PMID 9490697.
Thư viện PDB
| |
---|---|
Liên kết ngoài
1-50 | |
---|---|
51-100 | |
101-150 | |
151-200 | |
201-250 | |
251-300 | |
301-350 |